Introduction: Body image is an important developmental concern in adolescents and youth. Today, considering the cultural invasions by the Western societies in this age group, evaluating of body image seems necessary. According to its fundamental role in the creation of community health promotion and self-esteem among youth, so this study was conducted aimed to determine predictors of body image dissatisfaction among students of Qazvin University of Medical Sciences. Methods: In this cross-sectional study, we assessed 394 students of Qazvin University of Medical Sciences. Students completed two-part questionnaire (socio-demographic characteristics, BSQ). The Data were analyzed with descriptive and deductive statistic methods (Generalized Linear Models) at p<0.05 using SPSSv.16 software. Results: Mean of BSQ scores was 66.75 ± 29.80.The 288 students (72.2%) reported body image satisfaction and frequency of body image dissatisfaction was as mild (17.8%), moderate (8.5%), severe (1.5%). In univariate analyses, body image score mean was statistically related to BMI (r= 0.227, p<0.001). In regression analysis, gender (p<0.042), BMI (p<0.001) and weight decreasing diet (p<0.027) were related to Body image dissatisfaction. Conclusion: Regarding to this fact that girls are more dissatisfied with their body image compared with boys, interventional studies is recommended in increasing of body image satisfaction in this group that have a essential role in strength and survival of their families and communities. Also, due to the significant relationship between body mass index and body image dissatisfaction may be providing of education programs and sports facilities in a university setting and dormitory can improve students’ body image satisfaction.