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:: Volume 6, Issue 6 (February-March 2019) ::
IJPN 2019, 6(6): 48-56 Back to browse issues page
Effect of Medication Education on Drug Adherence with Mental Disorders: A Clinical Trial Study
Efat Sadeghian , Mina Nezafat dost , Lily Tapak , Farshid Shamsaei *
Hamadan University of Medical Sciences, Hamadan, Iran , shamsaei68@yahoo.com
Abstract:   (606 Views)
Introduction: One of the main goals of treatment in patients with mental disorders is compliance with drug therapy because non-compliance of the drug causes relapse of the disease and disrupts the treatment process. The purpose of this study was to investigate the effect of pharmacotherapy training on drug availability in patients with mental disorders.
Methods: In this clinical trial study, 80 patients with Mental Disorders diagnosed in Farshchian Hospital in Hamadan, Iran, from October to February 2017 participated. Participants in the study were randomly divided into two experimental (40) and control (40) groups. In the intervention group, medication education was administered in four sessions of an hour in group (each group of 10). The control group received routine nursing care. Patients' adherence with drug therapies was checked by using the checklist for observing drug compliance before and after the intervention. Data analysis was performed using descriptive and inferential statistics in SPSS software version 24.
Results: The two groups did not differ significantly in terms of personal characteristics (P > 0.05). Mean and standard deviation of drug compliance score before and after intervention in experimental group was 0.55 ± 4.03 and control group was1.50 ± 4.34, which did not show significant difference (P = 0.306). After the intervention, the difference in mean and standard deviation of drug adherence score was statistically significant in the experimental group (5.02 ± 3.27) and control (1.17 ± 3.53) (P < 0.001).
Conclusions: Medication education interventions have had a positive effect on drug dependence in patients with psychiatric disorders. Therefore, it is suggested that more attention be paid to educating patients about nursing care in nursing care programs.

Keywords: Education, Medication Therapy, Mental Patients, Medication Adherence
Full-Text [PDF 1519 kb]   (303 Downloads)    
Type of Study: Research | Subject: Special
Received: 2018/09/29
1. 1. Ghorayshizadeh MA, Kouchaksaraei F, Pezeshki M. Evaluation of Risk Factors of Relapse in Bipolar I Disorders and Its Relation to Demographic Feature. Med J Tabriz unit Med Sci. 2009;31(2):77-81.
2. Linsky A, Simon SR, Bokhour B. Patient perceptions of proactive medication discontinuation. Patient education and counseling. 2015;98(2):220-5. [DOI:10.1016/j.pec.2014.11.010] [PMID]
3. Fernández SG. Adherence to antipsychotic medication in bipolar disorder and schizophrenia patients: a systematic review. European Neuropsychopharmacology. 2016;26:S434. [DOI:10.1016/S0924-977X(16)31412-2]
4. Yadollahi S, Ashktorab T, Zayeri F. Medication Adherence and Related Factors in Patients with Epilepsy. Journal of hayat. 2015;21(2):67-80.
5. Sookhak F, Zolfaghari M, Asadi Noghabi AA, Haghani H. Effect of a cognitive-behavioral intervention on medication adherence in patients' undergoing hemodialysis. Journal of hayat. 2014;20(3):85-94.
6. Richardson M, Brennan G, James K, Lavelle M, Renwick L, Stewart D, et al. Describing the precursors to and management of medication nonadherence on acute psychiatric wards. General hospital psychiatry. 2015;37(6):606-12. [DOI:10.1016/j.genhosppsych.2015.06.017] [PMID]
7. Louis-Simonet M, Kossovsky MP, Sarasin FP, Chopard P, Gabriel V, Perneger TV, et al. Effects of a structured patient-centered discharge interview on patients' knowledge about their medications. The American journal of medicine. 2004;117(8):563-8. [DOI:10.1016/j.amjmed.2004.03.036] [PMID]
8. Coe AB, Moczygemba LR, Gatewood SB, Osborn RD, Matzke GR, Goode J-VR. Medication adherence challenges among patients experiencing homelessness in a behavioral health clinic. Research in Social and Administrative Pharmacy. 2015;11(3):e110-e20. [DOI:10.1016/j.sapharm.2012.11.004] [PMID] [PMCID]
9. DiBonaventura M, Gabriel S, Dupclay L, Gupta S, Kim E. A patient perspective of the impact of medication side effects on adherence: results of a cross-sectional nationwide survey of patients with schizophrenia. BMC psychiatry. 2012;12(1):20. [DOI:10.1186/1471-244X-12-20] [PMID] [PMCID]
10. Matsuda M, Kono A. Development and evaluation of a psychoeducation practitioner training program (PPTP). Archives of psychiatric nursing. 2015;29(4):217-22. [DOI:10.1016/j.apnu.2015.03.002] [PMID]
11. Ebrahimi H, Namdar H. The effect of therapeutic relationship in schizophrenic patients. Journal of Urmia Nursing And Midwifery Faculty. 2014;12(6):491-8.
12. Levin JB, Krivenko A, Bukach A, Tatsuoka C, Cassidy KA, Sajatovic M. A reexamination of non-psychiatric medication adherence in individuals with bipolar disorder and medical comorbidities. The Journal of nervous and mental disease. 2017;205(3):182. [DOI:10.1097/NMD.0000000000000544] [PMID] [PMCID]
13. Belzeaux R, Boyer L, Mazzola-Pomietto P, Michel P, Correard N, Aubin V, et al. Adherence to medication is associated with non-planning impulsivity in euthymic bipolar disorder patients. Journal of affective disorders. 2015;184:60-6. [DOI:10.1016/j.jad.2015.05.041] [PMID]
14. Shahin SH, Daly EB. Knowledge, attitudes and beliefs about psychotropic medication among Saudi hospitalized psychiatric patients. International journal of nursing studies. 1999;36(1):51-5. [DOI:10.1016/S0020-7489(98)00057-1]
15. El-Mallakh P, Findlay J. Strategies to improve medication adherence in patients with schizophrenia: the role of support services. Neuropsychiatric disease and treatment. 2015;11:1077. [DOI:10.2147/NDT.S56107] [PMID] [PMCID]
16. Costa E, Giardini A, Savin M, Menditto E, Lehane E, Laosa O, et al. Interventional tools to improve medication adherence: review of literature. Patient preference and adherence. 2015;9:1303. [DOI:10.2147/PPA.S87551] [PMID] [PMCID]
17. Holman H. Chronic disease—the need for a new clinical education. Jama. 2004;292(9):1057-9. [DOI:10.1001/jama.292.9.1057] [PMID]
18. Van Wijk BL, Klungel OH, Heerdink ER, de Boer A. Effectiveness of interventions by community pharmacists to improve patient adherence to chronic medication: a systematic review. Annals of Pharmacotherapy. 2005;39(2):319-28. [DOI:10.1345/aph.1E027] [PMID]
19. Stevenson FA, Cox K, Britten N, Dundar Y. A systematic review of the research on communication between patients and health care professionals about medicines: the consequences for concordance. Health expectations. 2004;7(3):235-45. [DOI:10.1111/j.1369-7625.2004.00281.x] [PMID] [PMCID]
20. Gleeson T, Iversen M, Avorn J, Brookhart A, Katz J, Losina E, et al. Interventions to improve adherence and persistence with osteoporosis medications: a systematic literature review. Osteoporosis international. 2009;20(12):2127-34. [DOI:10.1007/s00198-009-0976-0] [PMID] [PMCID]
21. Schedlbauer A, Davies P, Fahey T. Interventions to improve adherence to lipid lowering medication. 2010.
22. Schroeder K, Fahey T, Ebrahim S. Interventions for improving adherence to treatment in patients with high blood pressure in ambulatory settings. Cochrane Database Syst Rev. 2004(2):CD004804. [DOI:10.1002/14651858.CD004804]
23. Vergouwen A, Bakker A, Katon WJ, Verheij TJ, Koerselman F. Improving adherence to antidepressants: a systematic review of interventions. The Journal of clinical psychiatry. 2003;64(12):1415-20. [DOI:10.4088/JCP.v64n1203] [PMID]
24. Firooz M, Mazlom SR, Hoseini SJ, Hasanzadeh F, Kimiae SA, فیروز م, et al. Comparison between the effect of group education and group counseling on emotional self-care in type II diabetics. 2015.
25. Sadeghian E, Mogadam FA. Determination of factors affecting the medication compliance in patients admitted to psychiatric wards. 2005.
26. Rahmani F, Ebrahimi H, Ranjbar F, Razavi SS, Asghari E. The effect of group psychoeducation program on medication adherence in patients with bipolar mood disorders: A randomized controlled trial. Journal of caring sciences. 2016;5(4):287. [DOI:10.15171/jcs.2016.030] [PMID] [PMCID]
27. Javadpour A, Hedayati A, Dehbozorgi G-R, Azizi A. The impact of a simple individual psycho-education program on quality of life, rate of relapse and medication adherence in bipolar disorder patients. Asian journal of psychiatry. 2013;6(3):208-13. [DOI:10.1016/j.ajp.2012.12.005] [PMID]
28. Kunst EL, Mitchell M, Johnston AN. Manikin simulation in mental health nursing education: An integrative review. Clinical Simulation in Nursing. 2016;12(11):484-95. [DOI:10.1016/j.ecns.2016.07.010]
29. Dankert ME, Brensinger CM, Metzger KL, Li C, Koleva SG, Mesén A, et al. Attitudes of patients and family members towards implantable psychiatric medication. Schizophrenia research. 2008;105(1-3):279-86. [DOI:10.1016/j.schres.2008.05.008] [PMID]
30. Latter S, Yerrell P, Rycroft-Malone J, Shaw D. Nursing, medication education and the new policy agenda: the evidence base. International journal of nursing studies. 2000;37(6):469-79. [DOI:10.1016/S0020-7489(00)00026-2]
31. Bolster D, Manias E. Person-centred interactions between nurses and patients during medication activities in an acute hospital setting: qualitative observation and interview study. International journal of nursing studies. 2010;47(2):154-65 [DOI:10.1016/j.ijnurstu.2009.05.021] [PMID]
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sadeghian E, nezafat dost M, tapak L, shamsaei F. Effect of Medication Education on Drug Adherence with Mental Disorders: A Clinical Trial Study. IJPN. 2019; 6 (6) :48-56
URL: http://ijpn.ir/article-1-1257-en.html

Volume 6, Issue 6 (February-March 2019) Back to browse issues page
نشریه روان پرستاری Iranian Journal of  Psychiatric Nursing
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